Endocrine Abstracts

Background: Primary hyperaldosteronism is a common cause of secondary hypertension, accounting for up to 5% of cases locally. It is treated medically with spironolactone and/or amiloride, or surgically with adrenalectomy. This study determines the prognostic factors for response to treatment, resulting in reduction of blood pressure to normotensive levels.Methods: We retrospectively reviewed records of 57 patients who were diagnosed with primary hyperald...

Background: Primary adrenal insufficiency due to adrenal hemorrhage from anti-phospholipid syndrome (APS) is an uncommon and life threatening disorder. We present a case, highlighting the challenges in the diagnosis and management of this disorder.Case presentation: A 59-year-old Chinese lady presented with a 2-year history of bilateral flank pain, lethargy, poor appetite and weight loss. Initial blood investigations were unremarkable except for a choles...